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Bone Marrow Karyotype


Chromosome analysis is indicated in the individual suffering from particular kind of leukemia’s (e.g chronic myeloid leukemia) and other hematologic disorders. A chromosome analysis on bone marrow or leukemic blood may be helpful in the diagnosis of specific form of leukemia and/ or may aid in providing prognostic information. In patient who have had a bone marrow transplant, chromosome analysis may be useful in monitoring engraftment.



Methodology


Analysis G-banded karyotyping for the detection of numeric chromosome abnormalities as well as balanced and unbalanced chromosome rearrangements.



Specimen Requirement’s


Sample Type: Bone Marrow/ Peripheral Blood

Specimen Requirement:2-3 ml bone marrow aspirate in a Na-Hep (green top)

Specimen Stability: 24-48 hours from time of collection

Transport Condition:Ambient Temperature (2-8°C) with Cool pack

Turn Around Time (TAT):07-10 days



TESTS


Karyotype-Bone Marrow

Karyotype for Philadelphia Chromosome-Bone Marrow/Peripheral Blood

FISH- Her2/neu- Breast Cancer

FISH- BCR/ABL t(9;22)-CML