Karyotype or Chromosome analysis is a test that evaluated the number and structure of a person’s chromosome in order to detect abnormalities. Chromosome are thread like structures within each nucleus and contain the body’s genetic blueprint. Each chromosome contains thousands of genes in specific locations. These genes are responsible for person’s inherited physical characteristics and they have a profound impact on growth, development and function.
Humans have 46 chromosomes, present as 23 pairs. Twenty-two pairs are found in both genders (autosomes), and one pair (sex chromosome) is present as either XY (in males) or XX (in females). Normally. All cell in the body that have a nucleus will contain a complete set of the same chromosomes, except for the reproductive cells (eggs & sperm), which contain a half set of 23. This half set is the genetic contribution that will be passed on to a child. At conception, half set from each patent combine to form a new set of 46 chromosomes in the developing fetus. A karyotype test examines a person’s chromosome to determine if the right number is present and to determine if each chromosome appears normal.
Tests Summary (Karyotype)
Test Code | Test Name | Specimen Requirement | Sample Type | Specimen Stability | Transport Condition | Cost (INR) | Turn Around Time (TAT) Reports |
---|---|---|---|---|---|---|---|
KPB001 | Karyotype- Peripheral Blood (Adult) | 2-4 ml Blood in Na-Heparin (Green Top) vial | Peripheral Blood sample | Within 48-72 hours from time of collection | Ambient Temperature with cool pack (2-8˚C) | 2500 | 12-15 days |
KPB002 | Karyotype- Postnatal Pediatric (Child) | 2-4 ml Blood in Na-Heparin (Green Top) vial | Peripheral Blood sample | Within 48-72 hours from time of collection | Ambient Temperature with cool pack (2-8˚C) | 2500 | 12-15 days |
KPB003 | Karyotype- Ambiguous Genetilia | 2-4 ml Blood in Na-Heparin (Green Top) vial | Peripheral Blood sample | Within 48-72 hours from time of collection | Ambient Temperature with cool pack (2-8˚C) | 2500 | 12-15 days |
KPB004 | Karyotype- Couple (Husband & Wife) | 2-4 ml Blood in Na-Heparin (Green Top) vial | Peripheral Blood sample | Within 48-72 hours from time of collection | Ambient Temperature with cool pack (2-8˚C) | 4500 | 12-15 days |
KPB005 | Karyotype- Postnatal Cord Blood | 2-4 ml Blood in Na-Heparin (Green Top) vial | Peripheral Blood sample | Within 48-72 hours from time of collection | Ambient Temperature with cool pack (2-8˚C) | 3000 | 12-15 days |
KBM006 | Karyotype- Bone Marrow | 1-2 ml Bone Marrow Aspirate in Na-Heparin (Green Top) vial | Bone Marrow Aspirate | Within 24 hours from time of collection | Ambient Temperature with cool pack (2-8˚C) | 3500 | 12-15 days |
KPOC07 | Karyotype- Product of Conception (POC) | Placental/ fetal tissue (POC) in normal saline or transport medium (request lab) in sterile container | 25-50 mg placental tissue/ villus of fetal origin or skin (3 mm) with no maternal tissue contamination | Within 24 hours from time of collection | Ambient Temperature with cool pack (2-8˚C) | 6000 | 07-15 days |
KAF008* | Karyotype- Amniotic Fluid | Amniotic fluid in sterile screw capped (15 ml) centrifuge tube | 10-12 ml Amniotic fluid | Within 24 hours from time of collection | Ambient Temperature with cool pack (2-8˚C) | 8000 | 15-21 days |
KCVS09* | Karyotype- Chorionic Villus Sampling (CVS) | CVS / fetal tissue in transport medium (request lab) in sterile screw capped (15 ml) centrifuge tube | 20-40 mg placental tissue/ villus of fetal origin with no maternal tissue contamination | Within 24 hours from time of collection | Ambient Temperature with cool pack (2-8˚C) | 8000 | 15-21 days |